NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
Atlanta United
- OUT: Giorgos Giakoumakis (knee)
- OUT: Stian Gregersen (knee)
- OUT: Xande Silva (adductor)
Austin FC
- OUT: Leo Väisänen (foot)
- OUT: Žan Kolmanič (hamstring)
Charlotte FC
- OUT: Ben Bender (left knee)
- OUT: Brandon Cambridge (right ankle)
- QUESTIONABLE: Nathan Byrne (left thigh)
Chicago Fire FC
- OUT: Chase Gasper (leg)
- OUT: Andrew Gutman (leg)
FC Cincinnati
- OUT: London Aghedo (leg)
- OUT: Roman Celentano (ankle)
- OUT: Stiven Jimenez (foot)
Colorado Rapids
- OUT: Daniel Chacón (knee)
- OUT: Jonathan Lewis (knee)
- OUT: Connor Ronan (knee)
- OUT: Jasper Löffelsend (hamstring)
- QUESTIONABLE: Keegan Rosenberry (thigh)
Columbus Crew
- OUT: Christian Ramirez (thigh)
- OUT: Sean Zawadzki (head)
- QUESTIONABLE: Rudy Camacho (groin)
- QUESTIONABLE: Alex Matan (thigh)
FC Dallas
- OUT: Marco Farfan (head)
- OUT: Jesús Ferreira (hamstring)
- OUT: Asier Illarramendi (adductor)
- OUT: Geovane Jesus (right knee)
- OUT: Paxton Pomykal (knee)
- OUT: Alan Velasco (knee)
D.C. United
- OUT: Steven Birnbaum (knee)
- OUT: Russell Canouse (not due to injury)
- OUT: Nathan Crockford (head)
- OUT: Tyler Miller (shoulder)
- OUT: Garrison Tubbs (thigh)
Houston Dynamo FC
- OUT: Héctor Herrera (knee)
- OUT: Nelson Quiñónes (knee)
- QUESTIONABLE: Coco Carrasquilla (lower body)
- QUESTIONABLE: Sebastian Ferreira (lower body)
- QUESTIONABLE: Micael dos Santos (lower body)
Los Angeles Football Club
- OUT: Lorenzo Dellavalle (right knee)
LA Galaxy
- OUT: Jalen Neal (abdominal)
- OUT: Eriq Zavaleta (head)
Inter Miami CF
- OUT: Yannick Bright (hamstring)
- OUT: Facundo Farías (knee)
- OUT: Ian Fray (knee)
- OUT: Sergii Kryvtsov (hamstring)
- OUT: Federico Redondo (knee)
- OUT: Robbie Robinson (knee)
- OUT: Robert Taylor (hamstring)
Minnesota United FC
- OUT: Kervin Arriaga (knee)
- OUT: Emanuel Reynoso (not due to injury)
- OUT: Miguel Tapias (thigh)
- OUT: Zarek Valentin (thigh)
CF Montréal
- OUT: Mahala Opoku (ankle)
- OUT: Jules-Anthony Vilsaint (knee)
- QUESTIONABLE: Dominic Iankov (hamstring)
- QUESTIONABLE: Lassi Lappalainen (groin)
Nashville SC
- OUT: Randall Leal (hip)
- OUT: Shaq Moore (hip)
- OUT: Walker Zimmerman (knee)
- QUESTIONABLE: Tyler Boyd (hip)
- QUESTIONABLE: Lukas MacNaughton (hip)
New England Revolution
- OUT: Dylan Borrero (knee)
- OUT: Brandon Bye (knee)
- OUT: Peyton Miller (foot)
New York City FC
- OUT: Maxi Moralez (right knee)
- OUT: Talles Magno (knee)
- OUT: Jovan Mijatovic (not due to injury)
New York Red Bulls
- OUT: Cory Burke (groin)
- QUESTIONABLE: Emil Forsberg (hamstring)
Orlando City SC
- Matchday 8 bye
Philadelphia Union
- OUT: Leon Flach (left shoulder)
- OUT: Isaiah LeFlore (right knee)
- OUT: Holden Trent (hand)
- QUESTIONABLE: Andre Blake (head)
- QUESTIONABLE: Mikael Uhre (foot)
Portland Timbers
- OUT: Marvin Loria (knee)
- OUT: Larrys Mabiala (leg)
- OUT: Zac McGraw (head)
Real Salt Lake
- OUT: Kevin Bonilla (left knee)
- OUT: Erik Holt (hamstring)
- OUT: Pablo Ruiz (knee)
- OUT: Marcelo Silva (hamstring)
- QUESTIONABLE: Anderson Julio (hamstring)
San Jose Earthquakes
- OUT: Daniel (lower body)
- OUT: JT Marcinkowski (knee surgery)
- QUESTIONABLE: Michael Baldisimo (lower body)
- QUESTIONABLE: Vitor Costa (lower body)
- QUESTIONABLE: Jack Skahan (lower body)
- QUESTIONABLE: Amahl Pellegrino (lower body)
Seattle Sounders FC
- OUT: Reed Baker-Whiting (left hamstring)
- OUT: Léo Chú (knee)
- OUT: Pedro de la Vega (hamstring)
- OUT: Braudilio Rodrigues (right hamstring)
- QUESTIONABLE: João Paulo (left hip)
Sporting Kansas City
- OUT: Logan Ndenbe (knee)
- OUT: Johnny Russell (hamstring)
- QUESTIONABLE: Khiry Shelton (ankle)
St. Louis City SC
- OUT: Eduard Löwen (hamstring)
- OUT: Joakim Nilsson (ribs)
Toronto FC
- OUT: Lorenzo Insigne (thigh)
- OUT: Richie Laryea (thigh)
- OUT: Raoul Petretta (thigh)
- OUT: Brandon Servania (knee)
- QUESTIONABLE: Nickseon Gomis (wrist)
Vancouver Whitecaps FC
- OUT: Luís Martins (thigh)
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